İnşaat Mühendisliği Bölümü Yayın Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12416/395
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Article Citation - WoS: 17Citation - Scopus: 19Hydraulic Model Test Results of Baffle-Brush Fish Pass(Ice Publishing, 2015) Hassinger, Reinhard; Kucukali, SerhatThe flow characteristics (depth, velocity, energy dissipation) of a new baffle-brush fish pass were investigated experimentally in a 2 m wide rectangular flume which has a bed slope of 4% for discharges of 100-550 l/s. In all the experiments, quasi-uniform and sub-critical flow conditions and Froude numbers between 0.17 and 0.23 were observed. The Darcy-Weisbach friction factor was negatively correlated with the relative submergence of the brush elements. Two different characteristic velocity regions were identified, namely the baffle region and the brush region. The turbulence intensities were in the range 38-79% in the baffle zone and 13-31% in the brush zone. The hydraulic test results showed that this type of fish pass can produce adequate flow depth and favourable local flow velocities for the design discharge of 0.2 m(2)/s (relative submergence of brushes = 1.03), which is suitable for different fish species.Article Citation - WoS: 6Citation - Scopus: 8An Experimental Investigation of Flow Resistance and Turbulent Flow in Brush Fish Pass(Ice Publishing, 2019) Kucukali, SerhatThe present study aimed to search for chicken abdominal fat deposition-related polymorphisms within RB1 and to provide functional evidence for significantly associated genetic variants. Association analyses showed that 11 single nucleotide polymorphisms (SNPs) in intron 17 of RB1, were significantly associated with both abdominal fat weight (P < 0.05) and abdominal fat percentage (P < 0.05). Functional analysis revealed that the A allele of g.32828A>G repressed the transcriptional efficiency of RB1 in vitro, through binding nuclear factor-kappa B (NF-B-K) and SRY-related HMG box protein 2 (SOX2). Furthermore, RB1 mRNA expression levels in the abdominal fat tissue of individuals with the A/A genotype of g.32828A>G were lower than those of individuals with the G/G genotype. Collectively, we propose that the intronic SNP g.32828A>G of RB1 is an obesity-associated variant that directly affects binding with NF-B-K and SOX2, leading to changes in RB1 expression which in turn may influence chicken abdominal fat deposition.