Taşgın, Dilek IşıkUnaleroğlu, Canan2020-04-202020-04-202016Tasgin, Dilek Isik; Unaleroglu, Canan, "Ring annulation versus alkylation of pyrrole with alpha-phosphoryl-alpha,beta-unsaturated ketones", Tetrahedron, Vol. 72, No. 39, pp. 5934-5942, (2016).0040-4020https://hdl.handle.net/20.500.12416/3385In this study; novel aryl, heteroaryl, pyrrolyl and phosphoryl groups containing pyrrolizines were synthesized by the ring annulation reaction of aryl or heteroaryl substituted alpha-phosphoryl-alpha,beta-unsaturated ketones with pyrrole under mild reaction conditions. This domino reaction involves scandium triflate catalyzed addition of pyrrole to the double bond of alpha-phosphoryl-alpha,beta-unsaturated ketones, carbonyl group and finally ring annulation sequences. The presented work provided a convenient way for the synthesis of novel bispyrrolic compounds. (C) 2016 Elsevier Ltd. All rights reserved.eninfo:eu-repo/semantics/closedAccessPyrrolizinesPhosphonatesRing AnnulationMichael AdditionArticle72395934594210.1016/j.tet.2016.08.045