Yalçın, Y.D.Töral, T.B.Sukas, S.Yıldırım, E.Zorlu, Ö.Gündüz, U.Külah, H.06.06. Makine Mühendisliği06. Mühendislik Fakültesi01. Çankaya Üniversitesi2025-05-132025-05-1320199781733419000https://hdl.handle.net/20.500.12416/9883Chemical and Biological Microsystems Society (CBMS)This study presents label-free detection of imatinib resistance in K562 cells via integrated dielectrophoretic detection and impedimetric counting on a lab-on-a-chip system. Two impedimetric counting units were placed upstream and downstream of dielectrophoretic detection unit to obtain differential cell count and consequently the trapping ratio. The trapping ratio up to 57% was achieved for imatinib resistant (~60-fold) K562 cells, while it was minimized to 20% for wild type K562 cells. © 2019 CBMS-0001.eninfo:eu-repo/semantics/closedAccessDielectrophoresisImatinib ResistanceImpedimetric CountingLab-On-A-ChipLabel-Free DetectionConference Object2-s2.0-85094967961