Tasgin, Dilek IsikUnaleroglu, Canan09.01. Ortak Dersler Bölümü09. Rektörlük01. Çankaya Üniversitesi2020-04-202025-09-182020-04-202025-09-182016Tasgin, Dilek Isik; Unaleroglu, Canan, "Ring annulation versus alkylation of pyrrole with alpha-phosphoryl-alpha,beta-unsaturated ketones", Tetrahedron, Vol. 72, No. 39, pp. 5934-5942, (2016).0040-4020https://doi.org/10.1016/j.tet.2016.08.045https://hdl.handle.net/123456789/13025In this study; novel aryl, heteroaryl, pyrrolyl and phosphoryl groups containing pyrrolizines were synthesized by the ring annulation reaction of aryl or heteroaryl substituted alpha-phosphoryl-alpha,beta-unsaturated ketones with pyrrole under mild reaction conditions. This domino reaction involves scandium triflate catalyzed addition of pyrrole to the double bond of alpha-phosphoryl-alpha,beta-unsaturated ketones, carbonyl group and finally ring annulation sequences. The presented work provided a convenient way for the synthesis of novel bispyrrolic compounds. (C) 2016 Elsevier Ltd. All rights reserved.eninfo:eu-repo/semantics/closedAccessPyrrolizinesPhosphonatesRing AnnulationMichael AdditionArticle10.1016/j.tet.2016.08.0452-s2.0-84984630347