Browsing by Author "Aftab, Wasim"

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Citation - WoS: 1
Citation - Scopus: 1
Computational structural analysis for substituted nickel phthalocyanines preparation and characterization
(Revista Chimie Srl, 2016) Youssef, Tamer E.; Baleanu, Dumitru; Al Turaif, Hamad; Aftab, Wasim; Baleanu, Dumitru; Matematik
Hay synthesis of a novel series of symmetrically substituted nickel phthalocyanine derivatives, [(heterothio)(8)NiPcs] 4(a-e) bearing N-heterocycle moieties, i.e. Pyridine, Thiazoline, Imidazole, Tetrazole rings, was reported. Their novel heterocycle-thio phthalonitrile precursors 3(a-e) were synthesized by the aromatic nucleophilic substitution reaction of 4-nitrorophthalonitrile with N-heterocycle substituted thiols 2(a-e). The structure of the compounds was analyzed by the spectroscopic analysis tools. Besides, the powerful techniques of maximal wavelet discrete wavelet transformation together with boxplot clustering pointed out new aspects of the signals which cannot be detected by the spectroscopic analysis.
Citation - WoS: 2
Citation - Scopus: 2
On Classification of PDZ Domains: A Computational Study
(Hindawi Ltd, 2013) Aftab, Wasim; Baleanu, Dumitru; Memic, Adnan; Baleanu, Dumitru; 56389; Matematik
Our goal in this present study is to introduce new wavelet based methods for differentiating and classifying Class I and Class II PDZ domains and compare the resulting signals. PDZ domains represent one of the most common protein homology regions playing key roles in several diseases. To perform the classification, we developed two methods. The first of our methods was comparable to the standard wavelet approaches while the second one surpasses it in recognition accuracy. Our models exhibited interesting results, and we anticipate that it can be used as a computational technique to screen out the misfit candidates and to reduce the search space, while achieving high classification and accuracy.