PubMed İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12416/8650

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A new fractional wavelet approach for the simultaneous determination of ampicillin sodium and sulbactam sodium in a binary mixture
(Pergamon-elsevier Science Ltd, 2006) Dinç, E; Baleanu, Dumitru; Baleanu, DB; 6981
A new application of the fractional wavelet transform (FWT) was proposed for the simultaneous determination of ampicillin (AP) and sulbactam (SB) in a pharmaceutical combination for injection. FWT approach is a new powerful tool for removing noise and irrelevant information from the absorption spectra. Cardinal information having higher peak amplitude, eliminated noise, sharp peaks with shrinking width of spectral range was obtained by the application of FWT procedure to the original absorption spectra. In this paper, FWT approach was subjected to the data vector of the UV-signals obtained from AP and SB in the wavelength range of 211.5-313.8 nm. Derivative transform was applied to the original absorption signal together with its FWT generalization. The calibration graphs for AP and SB were obtained by measuring the FWT and usual derivative amplitudes at zero-crossing points. The method validation was carried out by using the synthetic mixture analysis. Our proposed FWT approach was compared with the usual derivative spectrophotometry and chemometric methods (CLS, PCR and PLS) and a good agreement was reported. (c) 2005 Elsevier B.V. All rights reserved.
An analysis on the relationship between safety awareness and safety behaviors of healthcare professionals, Ankara/Turkey
(Oxford Univ Press, 2020) Uzuntarla, Fatma; Kucukali, Serhat; Uzuntarla, Yasin; 20413
Objectives: This descriptive study aims to examine the relationship between the safety awareness of healthcare professional and their safety behaviors. Methods: The study was carried out on 418 healthcare professionals working in a training and research hospital in Ankara/Turkey. The survey method was used as data collection tool. The questionnaire consisted of 3 sections and 18 questions. First section consisted of questions on sociodemographic characteristics and, second section consisted of the awareness scale and third section consisted of safety behaviors scale. Results: The safety awareness and safety behaviors are scored on a scale from 1 (completely disagree) to 5 (completely agree). The safety awareness and safety behaviors has an average score of 3.85 +/- 0.81 and 3.56 +/- 0.82, respectively. The safety awareness and safety behavior levels of healthcare professionals were found to be high. Conclusion: A significant positive correlation was found between safety awareness and safety behaviors and it was concluded that the increase in safety awareness led to an increase in safety behavior.
An application of derivative and continuous wavelet transforms to the overlapping ratio spectra for the quantitative multiresolution of a ternary mixture of paracetamol, acetylsalicylic acid and caffeine in tablets
(Elsevier Science Bv, 2005) Dinç, E; Baleanu, Dumitru; Özdemir, A; Baleanu, D; 56389
Quantitative multi resolution of tablets and ternary mixtures of paracetamol (PAR), acetylsalicylic acid (ASP) and caffeine (CAF) having strongly overlapping spectra was accomplished by two graphical transform methods as ratio spectra first derivative-zero crossing and ratio spectra-continuous wavelet transform-zero crossing (ratio spectra CWT-zero crossing) methods. In this study, ratio spectra derivative-zero crossing and ratio spectra CWT-zero crossing methods are based on the use of transformed signals of the ratio spectra and their calibration graphs were obtained by measuring the dA/dlambda and CWT amplitudes of the ratio spectra corresponding to zero crossing points. For the comparison purpose. PLS calibration method was applied to predict the content of the same mixtures containing the subject active Compounds. The obtained calibrations were tested by using the synthetic mixtures and standard addition technique and they applied to the simultaneous determination of PAR, ASP and CAF in commercial pharmaceutical preparation. The obtained results were statistically compared with each other as well as those obtained by HPLC method and they showed good agreement. (C) 2004 Published by Elsevier B.V.
Analysis of reciprocity of cos-Gaussian and cosh-Gaussian laser beams in a turbulent atmosphere
(Optical Soc Amer, 2004) Eyyuboglu, HT; Baykal, Y; 7688; 7812
In a turbulent atmosphere, starting with a cos-Gaussian excitation at the source plane, the average intensity profile at the receiver plane is formulated. This average intensity profile is evaluated against the variations of link lengths, turbulence levels, two frequently used free-space optics wavelengths, and beam displacement parameters. We show that a cos-Gaussian beam, following a natural diffraction, is eventually transformed into a cosh-Gaussian beam. Combining our earlier results with the current findings, we conclude that cos-Gaussian and cosh-Gaussian beams act in a reciprocal manner after propagation in turbulence. The rates (paces) of conversion in the two directions are not the same. Although the conversion of cos-Gaussian beams to cosh-Gaussian beams can happen over a wide range of turbulence levels (low to moderate to high), the conversion of cosh-Gaussian beams to cos-Gaussian beams is pronounced under relatively stronger turbulence conditions. Source and propagation parameters that affect this reciprocity have been analyzed. (C) 2004 Optical Society of America.
Associated Factors of Psychological Symptoms Among Unemployed Turkish Adults: The Role of Personality Factors and Rumination
(Sage Publications inc, 2020) Tuna, Ezgi; Balci, Seyma; 163887
Unemployment has been associated with adverse mental health outcomes including depression and suicide. In the last decades, unemployment rates have increased substantially in Turkey; yet, factors and mechanisms that play a role in experiencing psychological symptoms among unemployed individuals are not well understood. The aim of this study was to investigate the role of personality characteristics on psychological symptoms among unemployed Turkish adults and to test the mediating role of rumination as a dysfunctional cognitive strategy. The sample consisted of 217 unemployed Turkish adults who completed self-report measures on neuroticism, external locus of control, rumination, and psychological symptoms. The results of the structural equation modeling indicated that rumination partially mediated the relationship between personality variables (i.e., neuroticism and external locus of control) and psychological symptoms, thus verifying the hypothesis of the study. The direct paths from trait neuroticism and external locus of control to psychological symptoms were also significant. Results revealed that a tendency to attribute future outcomes to external factors and an increased tendency to experience negative emotions are associated with engaging passively in rumination, which in turn predicts psychological symptoms. Interventions are suggested to focus on effective coping strategies along with increasing individuals' perceived control over life and future.
Attentional Control is Partially Impaired in Obstructive Sleep Apnea Syndrome
(Wiley, 2013) Tulek, Baykal; Atalay, Nart Bedin; Atalay, Nart Bedin; Kanat, Fikret; Suerdem, Mecit; 102366
Obstructive sleep apnea syndrome is associated with executive cognitive impairment. An important question is whether impairment in executive functioning in obstructive sleep apnea syndrome is independent of dysfunction in attention. Attentional control is a subcomponent of executive functioning that is mediated by frontal lobe processing. In the current study, we investigated whether attentional control is deficient in obstructive sleep apnea syndrome. Attentional control processes were investigated through conflict adaptation and conflict frequency paradigms. These neuropsychological paradigms were assessed by using the Simon, Flanker and Stroop tasks. We additionally analysed post-error slowing data within these tasks. Error processing is another index of cognitive control that is mediated by frontal lobe functioning. Our sample consisted of 14 healthy adults and 24 patients with untreated moderate-severe obstructive sleep apnea syndrome. Results indicated that attentional control is partially dysfunctional among patients with obstructive sleep apnea syndrome. Attentional control processes were deficient when focal attention (Flanker task) processes were involved, but were intact when observed using the Simon and Stroop tasks. A non-significant trend in post-error slowing data suggested that error processing, assessed with the Flanker task, was diminished among patients with obstructive sleep apnea syndrome. These results support the view that obstructive sleep apnea syndrome leads to some amount of frontal lobe dysfunction, and that attentional control and error processing might be particularly affected by obstructive sleep apnea syndrome.
Comparative spectral analysis of veterinary powder product by continuous wavelet and derivative transforms
(Pergamon-elsevier Science Ltd, 2007) Dinc, Erdal; Baleanu, Dumitru; Kanbur, Murat; Baleanu, Dumitru; 6981; 36107
Comparative simultaneous determination of chlortetracycline and benzocaine in the commercial veterinary powder product was carried out by continuous wavelet transform (CWT) and classical derivative transform (or classical derivative spectrophotometry). In this quantitative spectral analysis, two proposed analytical methods do not require any chemical separation process. In the first step, several wavelet families were tested to find an optimal CWT for the overlapping signal processing of the analyzed compounds. Subsequently, we observed that the coiflets (COIF-CWT) method with dilation parameter, a = 400, gives suitable results for this analytical application. For a comparison, the classical derivative spectrophotometry (CDS) approach was also applied to the simultaneous quantitative resolution of the same analytical problem. Calibration functions were obtained by measuring the transform amplitudes corresponding to zero-crossing points for both CWT and CDS methods. The utility of these two analytical approaches were verified by analyzing various synthetic mixtures consisting of chlortetracycline and benzocaine and they were applied to the real samples consisting of veterinary powder formulation. The experimental results obtained from the COIF-CWT approach were statistically compared with those obtained by classical derivative spectrophotometry and successful results were reported. (C) 2006 Elsevier B.V. All rights reserved.
Diffraction by a black half plane: Modified theory of physical optics approach
(Optical Soc Amer, 2005) Umul, YZ; Umul, Yusuf Ziya; 42699
The scattered fields from a black half plane which absorbs all the incoming electromagnetic energy are evaluated by defining a new modified theory of physical optics surface current. This current eliminates the reflected fields, coming from the first stationary point of the reflection integral and only creates a reflected diffracted field. The incident scattered fields are found from the same integral, written for the perfectly conducting half plane. The scattered fields are evaluated by using the stationary phase method and edge point technique. The evaluated fields are plotted numerically. (c) 2005 Optical Society of America.
Entropy-Functional-Based Online Adaptive Decision Fusion Framework With Application to Wildfire Detection in Video
(Ieee-inst Electrical Electronics Engineers inc, 2012) Gunay, Osman; Töreyin, Behçet Uğur; Toreyin, Behcet Ugur; Kose, Kivanc; Cetin, A. Enis; 19325
In this paper, an entropy-functional-based online adaptive decision fusion (EADF) framework is developed for image analysis and computer vision applications. In this framework, it is assumed that the compound algorithm consists of several subalgorithms, each of which yields its own decision as a real number centered around zero, representing the confidence level of that particular subalgorithm. Decision values are linearly combined with weights that are updated online according to an active fusion method based on performing entropic projections onto convex sets describing subalgorithms. It is assumed that there is an oracle, who is usually a human operator, providing feedback to the decision fusion method. A video-based wildfire detection system was developed to evaluate the performance of the decision fusion algorithm. In this case, image data arrive sequentially, and the oracle is the security guard of the forest lookout tower, verifying the decision of the combined algorithm. The simulation results are presented.
Equivalence of structure constants in non-Kolmogorov and Kolmogorov spectra
(Optical Soc Amer, 2011) Baykal, Yahya; Gercekcioglu, Hamza; 7812
We find the equivalence of the structure constants in non-Kolmogorov and Kolmogorov spectra in a turbulent atmosphere. As the reference point, the spherical wave scintillation index in a non-Kolmogorov medium is used. Relations of the structure constants are found to be functions of the power law of the turbulence spectrum and the Fresnel zone. It will be useful to employ the equivalence of the structure constants in making performance comparisons found with non-Kolmogorov and Kolmogorov spectra. (C) 2011 Optical Society of America
Equivalent functions for the Fresnel integral
(Optical Soc Amer, 2005) Umul, YZ; Umul, Yusuf Ziya; 42699
Fresnel integral is modeled with three equivalent functions. The first function is derived by considering the sum of the first term of the Fresnel integral's asymptotic expansion {(F) over cap (x)} and an exponential function which approaches to infinity at the zero of the Fresnel function's argument and has the properties of a unit step function. The second one is the sum of a unit step function and the transition function defined for the simplified uniform theory of diffraction. The third function considers directly eliminating the infinity coming from (F) over cap (x). The amplitude and the phase of Fresnel integral and its equivalent functions are compared numerically. The result is applied to the modified theory of physical optics solution of the diffraction of edge waves from a half plane problem. (c) 2005 Optical Society of America.
Flat topped beams and their characteristics in turbulent media
(Optical Soc Amer, 2006) Eyyuboglu, Halil Tanyer; Arpali, Caglar; Baykal, Yahya Kemal; 7688; 7812
The source and receiver plane characteristics of flat topped ( FT) beam propagating in turbulent atmosphere are investigated. To this end, source size, beam power and M(2) factor of source plane FT beam are derived. For a turbulent propagation medium, via Huygens Fresnel diffraction integral, the receiver plane intensity is found. Power captured within an area on the receiver plane is calculated. Kurtosis parameter and beam size variation along the propagation axis are formulated. Graphical outputs are provided displaying the variations of the derived source and receiver plane parameters against the order of flatness and propagation length. Analogous to free space behavior, when propagating in turbulence, the FT beam first will form a circular ring in the center. As the propagation length increases, the circumference of this ring will become narrower, giving rise to a downward peak emerging from the center of the beam, eventually turning the intensity profile into a pure Gaussian shape. (c) 2006 Optical Society of America.
H(D) -> D(H)+Cu(111) collision system: Molecular dynamics study of surface temperature effects
(Amer inst Physics, 2011) Vurdu, Can D.; Guvenc, Ziya B.
All the channels of the reaction dynamics of gas-phase H (or D) atoms with D (or H) atoms adsorbed onto a Cu(111) surface have been studied by quasiclassical constant energy molecular dynamics simulations. The surface is flexible and is prepared at different temperature values, such as 30 K, 94 K, and 160 K. The adsorbates were distributed randomly on the surface to create 0.18 ML, 0.28 ML, and 0.50 ML of coverages. The multi-layer slab is mimicked by a many-body embedded-atom potential energy function. The slab atoms can move according to the exerted external forces. Treating the slab atoms non-rigid has an important effect on the dynamics of the projectile atom and adsorbates. Significant energy transfer from the projectile atom to the surface lattice atoms takes place especially during the first impact that modifies significantly the details of the dynamics of the collisions. Effects of the different temperatures of the slab are investigated in this study. Interaction between the surface atoms and the adsorbates is modeled by a modified London-Eyring-Polanyi-Sato (LEPS) function. The LEPS parameters are determined by using the total energy values which were calculated by a density functional theory and a generalized gradient approximation for an exchange-correlation energy for many different orientations, and locations of one-and two-hydrogen atoms on the Cu(111) surface. The rms value of the fitting procedure is about 0.16 eV. Many different channels of the processes on the surface have been examined, such as inelastic reflection of the incident hydrogen, subsurface penetration of the incident projectile and adsorbates, sticking of the incident atom on the surface. In addition, hot-atom and Eley-Rideal direct processes are investigated. The hot-atom process is found to be more significant than the Eley-Rideal process. Furthermore, the rate of subsurface penetration is larger than the sticking rate on the surface. In addition, these results are compared and analyzed as a function of the surface temperatures. (c) 2011 American Institute of Physics. [doi:10.1063/1.3583811]
Mining Medlıne for the Treatment of Osteoporosis
(Springer, 2012) Yildirim, Pinar; Hassanpour, Reza; Ceken, Cinar; Hassanpour, Reza; Esmelioglu, Sadik; Tolun, Mehmet Resit; 101956
In this paper, we consider the importance of osteoporosis disease in terms of medical research and pharmaceutical industry and we introduce a knowledge discovery approach regarding the treatment of osteoporosis from a historical perspective. Osteoporosis is a systemic skeletal disease in which osteoporotic fractures are associated with substantial morbidity and mortality and impaired quality of life. Osteoporosis has also higher costs, for example, longer hospital stays than many other diseases such as diabetes and heart attack and it is an attractive market for pharmaceutical companies. We use a freely available biomedical search engine leveraging text-mining technology to extract the drug names used in the treatment of osteoporosis from MEDLINE articles. We conclude that alendronate (Fosamax) and raloxifene (Evista) have the highest number of articles in MEDLINE and seem the dominating drugs for the treatment of osteoporosis in the last decade.
Modified theory of physical optics
(Optica Publishing Group, 2004) Umul, YZ; Umul, Yusuf Ziya; 42699
A new procedure for calculating the scattered fields from a perfectly conducting body is introduced. The method is defined by considering three assumptions. The reflection angle is taken as a function of integral variables, a new unit vector, dividing the angle between incident and reflected rays into two equal parts is evaluated and the perfectly conducting (PEC) surface is considered with the aperture part, together. This integral is named as Modified Theory of Physical Optics (MTPO) integral. The method is applied to the reflection and edge diffraction from a perfectly conducting half plane problem. The reflected, reflected diffracted, incident and incident diffracted fields are evaluated by stationary phase method and edge point technique, asymptotically. MTPO integral is compared with the exact solution and PO integral for the problem of scattering from a perfectly conducting half plane, numerically. It is observed that MTPO integral gives the total field that agrees with the exact solution and the result is more reliable than that of classical PO integral. (C) 2004 Optical Society of America.
Modified theory of physical optics approach to wedge diffraction problems
(Optica Publishing Group, 2005) Umul, YZ; Umul, Yusuf Ziya; 42699
The problem of diffraction from a perfectly conducting wedge is examined with the modified theory of physical optics (MTPO). The exact wedge diffraction coefficient is compared with the asymptotic edge waves of MTPO integral and related surface currents are evaluated. The scattered electric fields are expressed by using these current components. The total, incident and reflected diffracted fields are compared with the exact series solution of the wedge problem, numerically. (C) 2005 Optical Society of America.
Modified theory of the physical-optics approach to the impedance wedge problem
(Optical Soc Amer, 2006) Umul, YZ; Umul, Yusuf Ziya; 42699
The problem of a wedge with equal face impedances is examined with a modified theory of physical optics. The surface integral is constructed by use of the impedance boundary condition. The aperture equivalent current is estimated from the behavior of the reflected diffracted field. The integrals obtained are evaluated asymptotically and compared with the exact solution numerically. (c) 2006 Optical Society of America.
Multidetermination of thiamine HC1 and pyridoxine HC1 in their mixture using continuous daubechies and biorthogonal wavelet analysis
(Elsevier Science Bv, 2003) Dinç, E; Baleanu, Dumitru; Baleanu, D; 56389
A new graphical method based on the one-dimensional wavelet transform (WT) was proposed and tested on mixture of thiamine hydrochloride (THI) and pyridoxine hydrochloride (PYR) in the presence of strongly overlapping signals. We selected from the data of the UV-VIS absorption spectra a signal consisting of 1150 points corresponding to the concentration range 8-32 mg ml(-1) for each vitamin and we subjected it to Daubechies8 (DAUB8) and Biorthogonal6.8 (BIOR6.8) wavelet transforms. Since the peaks of the transformed signals were bigger than original ones a zero crossing method was applied to obtain the calibration graphs. In addition, the validity of Beer-Lambert law was assumed for the transformed signals. An appropriate scale setting was choosing to obtain an alternative calibration for each method. MATLAB 6.5 software was used for one-dimensional wavelet analysis and the basic concepts about wavelet method were given. The obtained results were successfully compared among each other as well as with those obtained by other literature methods. The method developed in this paper is rapid, easy to apply, not expensive and it is suitable for analyzing of the overlapping signals of compounds in their mixtures without any chemical pre-treatment. (C) 2002 Elsevier Science B.V. All rights reserved.
Optimal control for a fractional tuberculosis infection model including the impact of diabetes and resistant strains
(Elsevier Science Bv, 2019) Sweilam, N. H.; Baleanu, Dumitru; AL-Mekhlafi, S. M.; Baleanu, D.; 56389
The objective of this paper is to study the optimal control problem for the fractional tuberculosis (TB) infection model including the impact of diabetes and resistant strains. The governed model consists of 14 fractional-order (FO) equations. Four control variables are presented to minimize the cost of interventions. The fractional derivative is defined in the Atangana-Baleanu-Caputo (ABC) sense. New numerical schemes for simulating a FO optimal system with Mittag-Leffler kernels are presented. These schemes are based on the fundamental theorem of fractional calculus and Lagrange polynomial interpolation. We introduce a simple modification of the step size in the two-step Lagrange polynomial interpolation to obtain stability in a larger region. Moreover, necessary and sufficient conditions for the control problem are considered. Some numerical simulations are given to validate the theoretical results. (C) 2019 The Authors. Published by Elsevier B.V. on behalf of Cairo University.
Phaseguide assisted liquid lamination for magnetic particle-based assays
(Royal Soc Chemistry, 2014) Phurimsak, Chayakom; Yıldırım, Ender; Yildirim, Ender; Tarn, Mark D.; Trietsch, Sebastiaan J.; Hankemeier, Thomas; Pamme, Nicole; Vulto, Paul; 31835
We have developed a magnetic particle-based assay platform in which functionalised magnetic particles are transferred sequentially through laminated volumes of reagents and washing buffers. Lamination of aqueous liquids is achieved via the use of phaseguide technology; microstructures that control the advancing air-liquid interface of solutions as they enter a microfluidic chamber. This allows manual filling of the device, eliminating the need for external pumping systems, and preparation of the system requires only a few minutes. Here, we apply the platform to two on-chip strategies: (i) a one-step streptavidin-biotin binding assay, and (ii) a two-step C-reactive protein immunoassay. With these, we demonstrate how condensing multiple reaction and washing processes into a single step significantly reduces procedural times, with both assay procedures requiring less than 8 seconds.

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