Scopus İndeksli Yayınlar Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12416/8651
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Article System-Level Prediction and Optimization of Cyclone Separator Performance Using a Hybrid CFD-DEM-ANN Approach(MDPI, 2026) Kocak, EyupIn this study, the separation performance of cyclone separators with different geometric configurations was investigated using a hybrid approach that combines Computational Fluid Dynamics, the Discrete Element Method, and Artificial Neural Networks. In the first stage, the flow field was solved using the Reynolds-Averaged Navier-Stokes equations together with the Reynolds Stress Model turbulence closure, and particle motion was evaluated in detail through DEM. To examine the effect of geometric parameters, the inlet aspect ratio, vortex finder diameter, and cylinder height were systematically assessed. The results revealed the formation of a pronounced Rankine-type vortex structure inside the cyclone and showed that secondary flow regions intensified as the vortex finder diameter and cylinder height increased, thereby reducing the separation efficiency. In the inlet section, an optimal aspect ratio was identified. In the second stage, an ANN model was developed to expand the limited dataset obtained from the CFD-DEM analyses. By optimizing the activation function and the number of neurons, the best performance was achieved with a ReLU-based neural network containing a single hidden neuron, reaching a test-set accuracy of approximately R2 approximate to 0.991 and an overall fit of R2 approximate to 0.895. The ANN model also captured interaction trends between flow velocity and geometry that could not be observed with the limited CFD dataset. This hybrid approach provides an effective and low-cost method for performance prediction and optimization in cyclone separator design.Article A Meta-Heuristic Stochastic Algorithm for the Numerical Treatment of Cancer Model through the Chemotherapy and Stem Cells(Elsevier, 2026) Baleanu, Dumitru; Defterli, Ozlem; Sabir, Zulqurnain; Abdelkawy, M. A.Objective: The aim of current research is to present the numerical performances of the cancer treatment model based on chemotherapy and stem cells using one of the heuristic computing neural network procedures. The cancer treatment model through chemotherapy and stem cells is categorized into stem cells, affected cells, tumor cells, and chemotherapy-based concentration drug. Method: A process of artificial neural network is applied using the hybrid optimization of global and local search schemes, which are taken as genetic algorithm (GA) and an active set (AS). An error-based fitness function is designed by using the differential model and then optimized by the hybridization of both global and local search schemes. GA is applied to exploit the global result and give a primary guess to the AS that further improves the results locally. AS is rooted in the GA, where GA produces new populaces and AS optimizes the fitness function for every individual. The hybridization of these two schemes is used iteratively for purifying the results. Ten numbers of neurons and log-sigmoid activation functions has been used to solve the cancer treatment model based on chemotherapy and stem cells. Results: For the correctness of the stochastic solver, the obtained numerical results have been compared with any traditional scheme. Moreover, the reliability and capability of the scheme are performed through the absolute error around 10-05 to 10-07 along with different statistical approaches for solving the mathematical model. Novelty: The proposed artificial neural network structure along with the hybrid optimization of global and local search schemes has never been implemented before to solve the cancer treatment model based on chemotherapy and stem cells.
