Yıldırım, Ender
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Makine Mühendisliği
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Scholarly Output
22
Articles
26
Citation Count
250
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0
22 results
Scholarly Output Search Results
Now showing 1 - 10 of 22
Article Citation - WoS: 11Citation - Scopus: 14Numerical study on effects of computational domain length on flow field in standing wave thermoacoustic couple(Elsevier Sci Ltd, 2019) Yıldırım, Ender; Mergen, Suhan; Yildirim, Ender; Türkoğlu, Haşmet; Turkoglu, Hasmet; Makine MühendisliğiFor the analysis of thermoacoustic (TA) devices, computational methods are commonly used. In the computational studies found in the literature, the flow domain has been modelled differently by different researchers. A common approach in modelling the flow domain is to truncate the computational domain around the stack, instead of modelling the whole resonator to save computational time. However, where to truncate the domain is not clear. In this study, we have investigated how the simulation results are affected by the computational domain length (I-d) when the truncated domain approach is used. For this purpose, a standing wave TA couple which undergoes a refrigeration cycle was considered. The stack plate thickness was assumed to be zero and the simulations were performed for six different dimensionless domain length (I-d/lambda) varying between 0.029 and 0.180. Frequency and Mach number were taken as 100 Hz and 0.01, respectively, and kept constant for all the cases considered. The mean pressure and the pressure amplitude were taken as 10 kPa and 170 Pa, respectively (Drive ratio of 1.7%). Helium was considered as the working fluid. To assess the accuracy of the simulation results, the pressure distributions across the domain were compared with that of the standing wave. In addition to the pressure variation, the effects of the domain length on the phase delay of the pressure and velocity waves along the stack plate were also investigated. The results showed that with the increasing I-d/lambda. ratio, the simulated pressure distribution compares better with the standing wave pressure distribution. With the lowest I-d/lambda ratio (0.029) considered, the difference between the amplitudes of the computed pressure distribution and theoretical standing wave pressure distribution was approximately 50 Pa. However, as I-d/lambda value increases, the simulation results approach to the theoretical standing wave pressure distribution better. The computational results obtained with Id/lambda = 0.132 and 0.180, were almost identical with standing wave acoustic field. Hence, it was concluded that the domain length has a significant effect on the accuracy of the computational results when the truncated domain approach is used. It was also observed that for a given TA device and operating parameters, there is a minimum I-d/lambda value for obtaining reliable results.Article Citation - WoS: 27Citation - Scopus: 30Investigation on replication of microfluidic channels by hot embossing(Taylor & Francis inc, 2017) Çoğun, Ferah; Cogun, Ferah; Yildirim, Ender; Yıldırım, Ender; Arikan, M. A. Sahir; 31835; Makine MühendisliğiIn this study, effects of embossing temperature, time, and force on production of a microfluidic device were investigated. Polymethyl methacrylate (PMMA) substrates were hot embossed by using a micromilled aluminum mold. The process parameters were altered to observe the variation of replication rate in width and depth as well as symmetry of the replicated microfluidic channels. Analysis of variance (ANOVA) on the experimental results indicated that embossing temperature was the most important process parameter, whereas embossing time and force have less impact. One distinguishing aspect of this study is that, the channels were observed to be skewed to either side of the channel depending on the location of the protrusions on the mold. The mechanism of the skewness was investigated by finite element analysis and discussed in detail. Results showed that the skewness depends on the flow characteristics of the material and could be reduced by increasing the embossing temperature. The best replication rates were obtained at parameter settings of 115 degrees C, 10kN, and 8min for the molds with minimum 56 mu m wide features of 120 mu m depth. We also showed that the fabricated channels could be successfully sealed by solvent-assisted thermo-compressive bonding at 85 degrees C under 5.5kN force.Article Citation - WoS: 28Citation - Scopus: 31SERS-Based Ultrafast and Sensitive Detection of Luteinizing Hormone In Human Serum Using A Passive Microchip(Elsevier Science Sa, 2018) Çoğun, Ferah; Gjergjizi, Belma; Cogun, Ferah; Yıldırım, Ender; Yildirim, Ender; Eryilmaz, Merve; Selbes, Yesim; Saglam, Necdet; Tamer, Ugur; 3837; Makine MühendisliğiHuman luteinizing hormone (LH) is an important analyte for doping control analysis since it increases the athletic performance. However, traditional methods to detect LH have few disadvantages, such as long analysis duration, waste disposal problem and sample matrix effect. Addressing these problems, surface enhanced Raman spectroscopy based LH analysis using a passive microfluidic chip was developed and optimized. Antibody modified magnetic gold nanoparticles captured the LH and then, 4-aminothiophenol (4-ATP) labeled nanoparticles formed the sandwich immunoassay structure. The complex and the other reactions occurred in different chambers of the chip. The SERS signals of 4-ATP were recorded from the chamber and the system was shown to detect 0.036 IU L-1 in serum samples. The performance of the immunoassay was compared to all other methods and the proposed assay was the fastest analysis of LH without any problems associated with the sensitivity. The shorter analysis time was recorded because the chip enables the control of all reactions in one place and there was no requirement of a specialized laboratory. (c) 2018 Elsevier B.V. All rights reserved.Conference Object Microchip Based Determination of Bacteria by In Chip Sandwich Immunoassay International Multidisciplinary Symposium on Drug Research and Development(2015) Çoğun, Ferah; Yıldırım, Ender; Yıldırım, Ender; Boyacı, İsmail Hakkı; Çetin, Demet; Suludere, Zekiye; Tamer, Uğur; Ertaş, Nusret; Makine MühendisliğiConference Object Citation - Scopus: 0Phaseguide assisted liquid lamination for magnetic bead-based assays(Chemical and Biological Microsystems Society, 2013) Phurimsak, C.; Yıldırım, Ender; Yildirim, E.; Trietsch, S.J.; Hankemeier, T.; Tarn, M.D.; Pamme, N.; Vulto, P.; Makine MühendisliğiWe demonstrate a simple, pump-free platform for performing rapid magnetic bead-based processes via their transfer through sequentially laminated liquid streams, made possible by the use of phaseguide technology. We have applied this strategy to two on-chip assays: (i) a streptavidin-biotin binding assay, and (ii) a sandwich immunoassay for the detection of C-reactive protein (CRP). Here, functionalized magnetic beads were pulled through alternating lanes of reagents and buffer solution, allowing multiple binding and washing processes to be reduced into a single step, significantly shortening procedural times compared to conventional multi-step bead-based assays.Conference Object Simultaneous Detection of Two Different Bacteria Using QDs and MNPs(2016) Çoğun, Ferah; Yıldırım, Ender; Çoğun, Ferah; Yıldırım, Ender; Çetin, Demet; Suludere, Zekiye; Boyacı, İsmail Hakkı; Ertaş, Nusret; Tamer, Uğur; Makine MühendisliğiArticle Citation - WoS: 7Citation - Scopus: 8A novel zero-dead-volume sample loading interface for microfluidic devices: flexible hydraulic reservoir (FHR)(Iop Publishing Ltd, 2018) Hatipoglu, Utku; Yıldırım, Ender; Cetin, Barbaros; Yildirim, Ender; 158278; 31835; Makine MühendisliğiInfusing minute amounts of valuable liquids such as samples to microfluidic chips by using common pumping schemes such as syringe pumps often result in an excessive dead-volume. We present a simple yet effective sample loading interface, which helps by pumping the sample to the chip by using the hydraulic pressure generated by the syringe pump. Results show that sample volumes as low as 25 mu l can be delivered at flow rates ranging between 10-30 mu l min(-1). Maximum dead volume ratio was observed to be 3% when infusing 200 mu l of sample at 10 mu l min(-1).Conference Object Citation - WoS: 12Citation - Scopus: 13A Reconfigurable Microfluidic Transmitarray Unit Cell(Ieee, 2013) Erdil, Emre; Yıldırım, Ender; Topalli, Kagan; Zorlu, Ozge; Toral, Taylan; Yildirim, Ender; Kulah, Haluk; Civi, Ozlem Aydin; 31835); Makine MühendisliğiThis paper presents a novel microfluidics based approach to develop a reconfigurable circularly polarized transmitarray unit cell. The unit cell comprises double layer nested split ring slots formed as microfluidic channels that can be filled by fluids. Split regions in the slots are realized by injecting liquid metal into the channels. Beam steering is obtained by implementing rotational phase shifting via manipulating the liquid metal in the slots. X-band unit cell prototypes are fabricated on glass substrate carrying a patterned metal film, and the slot channels are formed by Polydimethylsiloxane (PDMS) using soft lithography techniques.Article Citation - WoS: 43Citation - Scopus: 54A normally closed electrostatic parylene microvalve for micro total analysis systems(Elsevier Science Sa, 2012) Yildirim, Ender; Yıldırım, Ender; Arikan, M. A. Sahir; Kulah, Haluk; 120121; Makine MühendisliğiThis paper presents an electrostatically actuated, normally closed microvalve for parylene microfluidics. The proposed valve structure isolates the fluid from the electric field, and hence results in relatively low actuation potentials (<60 V) irrespective of the working fluid. Hereby, the microvalve solves electrolysis or electrode shielding problems observed in electrostatic actuation in micro total analysis systems. To investigate leakage properties, microvalves were tested under pressurized flow with de-ionized (DI) water. No detectable leakage ratio was observed up to 20 kPa inlet pressure, due to the unique semicircular valve seat design. It was shown that the valve seat could be reconfigured to enable sealing at various pressure levels for different applications. (C) 2012 Elsevier B.V. All rights reserved.Conference Object Citation - WoS: 0Citation - Scopus: 0Fluorescent on-chip imager by using a tunable absorption filter(Ieee, 2017) Arpali, Caglar; Yıldırım, Ender; Yildirim, Ender; Arpali, Serap Altay; 20809; 31835; 51304; Makine Mühendisliği
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