Phaseguides as Tunable Passive Microvalves for Liquid Routing in Complex Microfluidic Networks
| dc.contributor.author | Trietsch, Sebastiaan J. | |
| dc.contributor.author | Joore, Jos | |
| dc.contributor.author | van den Berg, Albert | |
| dc.contributor.author | Hankemeier, Thomas | |
| dc.contributor.author | Vulto, Paul | |
| dc.contributor.author | Yildirim, Ender | |
| dc.contributor.authorID | 31835 | tr_TR |
| dc.contributor.other | 01. Çankaya Üniversitesi | |
| dc.contributor.other | 06. Mühendislik Fakültesi | |
| dc.contributor.other | 06.06. Makine Mühendisliği | |
| dc.date.accessioned | 2017-06-09T08:43:16Z | |
| dc.date.accessioned | 2025-09-18T16:08:35Z | |
| dc.date.available | 2017-06-09T08:43:16Z | |
| dc.date.available | 2025-09-18T16:08:35Z | |
| dc.date.issued | 2014 | |
| dc.description | Yildirim, Ender/0000-0002-7969-2243; Hankemeier, Thomas/0000-0001-7871-2073; Joore, Jos/0000-0002-2744-4862; Van Den Berg, Albert/0000-0001-9019-933X | en_US |
| dc.description.abstract | A microfluidic passive valving platform is introduced that has full control over the stability of each valve. The concept is based on phaseguides, which are small ridges at the bottom of a channel acting as pinning barriers. It is shown that the angle between the phaseguide and the channel sidewall is a measure of the stability of the phaseguide. The relationship between the phaseguide-wall angle and the stability is characterized numerically, analytically and experimentally. Liquid routing is enabled by using multiple phaseguide with different stability values. This is demonstrated by filling complex chamber matrices. As an ultimate demonstration of control, a 400-chamber network is used as a pixel array. It is the first time that differential stability is demonstrated in the realm of passive valving. It ultimately enables microfluidic devices for massive data generation in a low-cost disposable format. | en_US |
| dc.description.sponsorship | Technology Foundation STW; Netherlands Metabolomics Centre; Scientific and Technological Research Council of Turkey | en_US |
| dc.description.sponsorship | Authors like to thank Koen Sweering and Athanasios Giannitsis for fabrication of microfluidic chips. Our gratitude also goes to the Technology Foundation STW, the Netherlands Metabolomics Centre and the Scientific and Technological Research Council of Turkey for funding this research. | en_US |
| dc.identifier.citation | Yıldırım, E...et al. (2014). Phaseguides as tunable passive microvalves for liquid routing in complex microfluidic networks. Lab On A Chip, 14(17). 3334-3340. http://dx.doi.org/10.1039/c4lc00261j | en_US |
| dc.identifier.doi | 10.1039/c4lc00261j | |
| dc.identifier.issn | 1473-0197 | |
| dc.identifier.issn | 1473-0189 | |
| dc.identifier.scopus | 2-s2.0-84905457590 | |
| dc.identifier.uri | https://doi.org/10.1039/c4lc00261j | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12416/15111 | |
| dc.language.iso | en | en_US |
| dc.publisher | Royal Soc Chemistry | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.title | Phaseguides as Tunable Passive Microvalves for Liquid Routing in Complex Microfluidic Networks | en_US |
| dc.title | Phaseguides as tunable passive microvalves for liquid routing in complex microfluidic networks | tr_TR |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| gdc.author.id | Yildirim, Ender/0000-0002-7969-2243 | |
| gdc.author.id | Hankemeier, Thomas/0000-0001-7871-2073 | |
| gdc.author.id | Joore, Jos/0000-0002-2744-4862 | |
| gdc.author.id | Van Den Berg, Albert/0000-0001-9019-933X | |
| gdc.author.institutional | Yıldırım, Ender | |
| gdc.author.scopusid | 36165070100 | |
| gdc.author.scopusid | 36140767300 | |
| gdc.author.scopusid | 6603388696 | |
| gdc.author.scopusid | 7201501215 | |
| gdc.author.scopusid | 8560890900 | |
| gdc.author.scopusid | 9332533100 | |
| gdc.author.wosid | Van Den Berg, Albert/B-4648-2013 | |
| gdc.author.wosid | Yıldırım, Ender/K-3962-2019 | |
| gdc.author.wosid | Hankemeier, Thomas/V-5407-2019 | |
| gdc.description.department | Çankaya University | en_US |
| gdc.description.departmenttemp | [Yildirim, Ender; Trietsch, Sebastiaan J.; Hankemeier, Thomas; Vulto, Paul] Leiden Univ, Leiden Acad Ctr Drug Res, Div Analyt Biosci, NL-2300 RA Leiden, Netherlands; [Yildirim, Ender] Cankaya Univ, Dept Mech Engn, TR-06810 Ankara, Turkey; [Trietsch, Sebastiaan J.; Joore, Jos; Vulto, Paul] MIMETAS BV, NL-2301 EA Leiden, Netherlands; [van den Berg, Albert] Univ Twente, MESA Inst Nanotechnol, NL-7500 AE Enschede, Netherlands | en_US |
| gdc.description.endpage | 3340 | en_US |
| gdc.description.issue | 17 | en_US |
| gdc.description.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| gdc.description.scopusquality | Q1 | |
| gdc.description.startpage | 3334 | en_US |
| gdc.description.volume | 14 | en_US |
| gdc.description.woscitationindex | Science Citation Index Expanded | |
| gdc.description.wosquality | Q1 | |
| gdc.identifier.openalex | W2160365984 | |
| gdc.identifier.pmid | 24989781 | |
| gdc.identifier.wos | WOS:000340204300027 | |
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