PubMed İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12416/8650

Browse

Now showing 1 - 2 of 2

Citation - WoS: 8
Citation - Scopus: 8
Continuous Wavelet Transform Applied To the Quantitative Analysis of a Binary Mixture
(Revista Chimie Srl, 2009) Dinc, Erdal; Baleanu, Dumitru; Baleanu, Dumitru; Üstündag, Ö; Aboul-Enein, HY; Matematik
Signal processing methods, continuous wavelet transform (CWT) methods, were proposed for the simultaneous spectral determination of ampicillin sodium (AS) and sulbactam sodium (SS) in their synthetic binary mixtures and pharmaceutical preparations. Firstly, the ratio spectra were obtained by dividing the absorption spectra of a pure compound and its binary mixture by a standard spectrum of one of the compounds in binary mixture. Secondly, the ratio spectra of AS, SS and their samples were processed by the Mexican hat-CWT and Symtles3-CWT (MEX-CWT and SYM3-CWT, respectively). hi this application, the MEX and SYM3 among wavelet families were found to be optimal to obtain the highest spectral recoveries. Calibration graphs of AS and SS in the linear concentration range of 10-70 mu g/mL and 10-55 mu g/mL were obtained by measuring the amplitudes of the transformed ratio signals, respectively. Percent mean recoveries obtained by application of the CWT methods to the synthetic mixtures were found between 99.1 % and 103.6 %. Both SYM3-CWT and MEX-CWT methods were applied to the real samples containing two active compounds and successful results were obtained.
Citation - WoS: 13
Citation - Scopus: 14
Continuous Wavelet Transformation Applied To the Simultaneous Quantitative Analysis of Two-Component Mixtures
(Govi-verlag Pharmazeutischer verlag Gmbh, 2004) Dinç, E; Baleanu, Dumitru; Baleanu, D; Üstündag, Ö; Aboul-Enein, HY; Matematik
In this paper we developed a graphical method based on Haar (HA) and Mexican (MEX) one-dimensional continuous wavelet transforms and we applied it to a mixture of hydrochlorothiazide (HCT) and spironolactone (SP) in the presence of strongly overlapping signals. Keeping in mind to obtain an appropriately transformed spectrum, we tested several values of the scaling parameter a and the point number of the analysed spectrum in the concentration range of 2-22 mug/ml for both active compounds. The optimal values of the scale parameters and the corresponding frequencies were found to be a = 32 and 0.031 for HA and a = 30 and 0.008 for MEX corresponding to 400 points. HA and MEX methods based on a zero crossing technique were applied to the analysed signal and their regression lines at the selected points were obtained. The validation of the above methods was carried out by analysing different synthetic mixtures containing HCT and SP. MATLAB 6.5. Software was used for one-dimensional wavelet analysis and the basic concepts about wavelet method were briefly explained. The method developed in this paper is rapid, easy to apply, inexpensive and is suitable for analysing the overlapping signals of compounds in their mixtures without any chemical pre-treatment.

Browse

Browsing PubMed İndeksli Yayınlar Koleksiyonu by Author "Aboul-Enein, HY"