Kimya Bilim Dalı
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12416/2168
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Article Citation - WoS: 5Citation - Scopus: 6Ring annulation versus alkylation of pyrrole with alpha-phosphoryl-alpha,beta-unsaturated ketones(Pergamon-elsevier Science Ltd, 2016) Tasgin, Dilek Isik; Unaleroglu, Canan; 16910In this study; novel aryl, heteroaryl, pyrrolyl and phosphoryl groups containing pyrrolizines were synthesized by the ring annulation reaction of aryl or heteroaryl substituted alpha-phosphoryl-alpha,beta-unsaturated ketones with pyrrole under mild reaction conditions. This domino reaction involves scandium triflate catalyzed addition of pyrrole to the double bond of alpha-phosphoryl-alpha,beta-unsaturated ketones, carbonyl group and finally ring annulation sequences. The presented work provided a convenient way for the synthesis of novel bispyrrolic compounds. (C) 2016 Elsevier Ltd. All rights reserved.Article Citation - WoS: 3Citation - Scopus: 3N-phosphorylation of pyrroles: An intramolecular migration reaction(Pergamon-elsevier Science Ltd, 2018) Tasgin, Dilek Isik; Taşgın, Dilek; Unaleroglu, Canan; Ortak Dersler BölümüA new synthetic method is reported for the N-phosphorylation of pyrroles via intramolecular migration of a phosphonate diester group. The reaction proceeds under mild conditions and produces N-phosphorylated pyrrole derivatives in moderate to good yields. (C) 2018 Elsevier Ltd. All rights reserved.