Dielectrophoretic Detection of Imatinib Resistance in K562 Cells Using a Lab-On System
| dc.contributor.author | Yalçın, Y.D. | |
| dc.contributor.author | Töral, T.B. | |
| dc.contributor.author | Sukas, S. | |
| dc.contributor.author | Yıldırım, E. | |
| dc.contributor.author | Zorlu, Ö. | |
| dc.contributor.author | Gündüz, U. | |
| dc.contributor.author | Külah, H. | |
| dc.contributor.other | 06.06. Makine Mühendisliği | |
| dc.contributor.other | 06. Mühendislik Fakültesi | |
| dc.contributor.other | 01. Çankaya Üniversitesi | |
| dc.date.accessioned | 2025-05-13T13:27:37Z | |
| dc.date.available | 2025-05-13T13:27:37Z | |
| dc.date.issued | 2019 | |
| dc.description | Chemical and Biological Microsystems Society (CBMS) | en_US |
| dc.description.abstract | This study presents label-free detection of imatinib resistance in K562 cells via integrated dielectrophoretic detection and impedimetric counting on a lab-on-a-chip system. Two impedimetric counting units were placed upstream and downstream of dielectrophoretic detection unit to obtain differential cell count and consequently the trapping ratio. The trapping ratio up to 57% was achieved for imatinib resistant (~60-fold) K562 cells, while it was minimized to 20% for wild type K562 cells. © 2019 CBMS-0001. | en_US |
| dc.description.sponsorship | Türkiye Bilimsel ve Teknolojik Araştirma Kurumu, TÜBITAK, (1150085, 2211E) | en_US |
| dc.identifier.isbn | 9781733419000 | |
| dc.identifier.scopus | 2-s2.0-85094967961 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12416/9883 | |
| dc.language.iso | en | en_US |
| dc.publisher | Chemical and Biological Microsystems Society | en_US |
| dc.relation.ispartof | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 -- 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 -- 27 October 2019 through 31 October 2019 -- Basel -- 163704 | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Dielectrophoresis | en_US |
| dc.subject | Imatinib Resistance | en_US |
| dc.subject | Impedimetric Counting | en_US |
| dc.subject | Lab-On-A-Chip | en_US |
| dc.subject | Label-Free Detection | en_US |
| dc.title | Dielectrophoretic Detection of Imatinib Resistance in K562 Cells Using a Lab-On System | en_US |
| dc.type | Conference Object | en_US |
| dspace.entity.type | Publication | |
| gdc.author.institutional | Yıldırım, Ender | |
| gdc.author.scopusid | 57208089165 | |
| gdc.author.scopusid | 55816398800 | |
| gdc.author.scopusid | 25722362600 | |
| gdc.author.scopusid | 36165070100 | |
| gdc.author.scopusid | 15023827100 | |
| gdc.author.scopusid | 26643388500 | |
| gdc.author.scopusid | 26643388500 | |
| gdc.description.department | Çankaya University | en_US |
| gdc.description.departmenttemp | Yalçın Y.D., Middle East Technical University, Ankara, Turkey, Mikro Biyosistemler Electronics Inc., Ankara, Turkey; Töral T.B., Mikro Biyosistemler Electronics Inc., Ankara, Turkey; Sukas S., Mikro Biyosistemler Electronics Inc., Ankara, Turkey, Department of Chemical Engineering, Vrije Universiteit Brussel, Brussel, Belgium; Yıldırım E., Mikro Biyosistemler Electronics Inc., Ankara, Turkey, Çankaya University, Ankara, Turkey; Zorlu Ö., Mikro Biyosistemler Electronics Inc., Ankara, Turkey; Gündüz U., Middle East Technical University, Ankara, Turkey; Külah H., Middle East Technical University, Ankara, Turkey, Mikro Biyosistemler Electronics Inc., Ankara, Turkey, METU MEMS Center, Ankara, Turkey | en_US |
| gdc.description.endpage | 1359 | en_US |
| gdc.description.publicationcategory | Konferans Öğesi - Uluslararası - Kurum Öğretim Elemanı | en_US |
| gdc.description.scopusquality | N/A | |
| gdc.description.startpage | 1358 | en_US |
| gdc.description.wosquality | N/A | |
| gdc.scopus.citedcount | 0 | |
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